DeCS Server - List Exact Term

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DeCS

Descriptor English:

beta Karyopherins

Descriptor Spanish:

beta Carioferinas

Descriptor Portuguese:

beta Carioferinas

Synonyms English:

Karyopherin-beta

Tree Number:

Definition English:

Nucleocytoplasmic transport molecules that bind to ALPHA KARYOPHERINS in the CYTOSOL and are involved in transport of molecules through the NUCLEAR PORE COMPLEX. Once inside the CELL NUCLEUS beta karyopherins interact with RAN GTP-BINDING PROTEIN and dissociate from alpha karyopherins. Beta karyopherins bound to RAN GTP-BINDING PROTEIN are then re-transported to the cytoplasm where hydrolysis of the GTP of RAN GTP-BINDING PROTEIN causes release of karyopherin beta.

History Note English:

2002; use BETA KARYOPHERINS (NM) 1995-2001; for IMPORTIN-BETA use KARYOPHERINS (NM) 1995-2001

Allowable Qualifiers English:

Record Number:

36193

Unique Identifier:

D028961

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